TY  - GEN
N2  - Substance use disorder is a chronic, often relapsing disease that can include a loss of behavioral inhibition and compulsive drug-seeking. Acquisition of a reward seeking behavior often begins when cues are paired with rewards. These cues are thought to influence subsequent extinction (animal model of exposure-based therapy) and relapse-like behavior, both in humans and animals. My work found that acquisition and extinction of cocaine-induced conditioned place preference (CPP) were sensitive to the configuration of the apparatus and that the dorsal hippocampus (DH) regulated expression of CPP after acquisition and extinction.
DO  - 10.6083/m4hm580w
DO  - DOI
AB  - Substance use disorder is a chronic, often relapsing disease that can include a loss of behavioral inhibition and compulsive drug-seeking. Acquisition of a reward seeking behavior often begins when cues are paired with rewards. These cues are thought to influence subsequent extinction (animal model of exposure-based therapy) and relapse-like behavior, both in humans and animals. My work found that acquisition and extinction of cocaine-induced conditioned place preference (CPP) were sensitive to the configuration of the apparatus and that the dorsal hippocampus (DH) regulated expression of CPP after acquisition and extinction.
T1  - Involvement of the dorsal hippocampus and histone deacetylase 3 in reward-seeking behaviors
DA  - 2017
AU  - Hitchcock, Leah
L1  - https://digitalcollections.ohsu.edu/record/7573/files/Hitchcock.Leah.2017.pdf
PB  - Oregon Health and Science University
PY  - 2017
ID  - 7573
L4  - https://digitalcollections.ohsu.edu/record/7573/files/Hitchcock.Leah.2017.pdf
KW  - Hippocampus
KW  - Learning
KW  - Reward
KW  - Behavioral Sciences
KW  - histone deacetylase 3
TI  - Involvement of the dorsal hippocampus and histone deacetylase 3 in reward-seeking behaviors
Y1  - 2017
L2  - https://digitalcollections.ohsu.edu/record/7573/files/Hitchcock.Leah.2017.pdf
LK  - https://digitalcollections.ohsu.edu/record/7573/files/Hitchcock.Leah.2017.pdf
UR  - https://digitalcollections.ohsu.edu/record/7573/files/Hitchcock.Leah.2017.pdf
ER  -