000007585 001__ 7585 000007585 005__ 20251007005912.0 000007585 0247_ $$2DOI$$a10.6083/fq977v472 000007585 037__ $$aETD 000007585 245__ $$aVarGraph: a decision support tool for variant classification using pathway databases 000007585 260__ $$bOregon Health and Science University 000007585 269__ $$a2019 000007585 336__ $$aCapstone 000007585 502__ $$bM.S. 000007585 502__ $$gBioinformatics & Computational Biomedicine 000007585 520__ $$aGenomic screening is an increasingly important part of cancer care. Screening often detects somatic variants in the tumor sample of varied clinical significance: some are well understood, some are connected to only loose evidence, and some are unknown altogether. The purpose of this project was to construct a tool that could present state-of-the-art pathway information to genomics experts evaluating the clinical significance of variants. 000007585 542__ $$fIn copyright - single owner 000007585 650__ $$aGenomics$$033016 000007585 650__ $$aSoftware$$026159 000007585 650__ $$aNeoplasms$$022758 000007585 650__ $$aDatabases, Genetic$$033839 000007585 691__ $$aSchool of Medicine$$041369 000007585 692__ $$aDepartment of Medical Informatics and Clinical Epidemiology$$041422 000007585 7001_ $$uOregon Health and Science University$$041354$$10000-0002-0985-1923$$aBall, David 000007585 7201_ $$uOregon Health and Science University$$041354$$7Personal$$eAdvisor$$aWu, Guanming 000007585 8564_ $$95d74080b-22e6-4edf-b967-40ee658fa006$$s2873489$$uhttps://digitalcollections.ohsu.edu/record/7585/files/ball.david._2019.pdf$$ePublic$$2af466add007c8db4cf810380e66ead81$$31 000007585 905__ $$a/rest/prod/fq/97/7v/47/fq977v472 000007585 909CO $$ooai:digitalcollections.ohsu.edu:7585$$pstudent-work 000007585 980__ $$aTheses and Dissertations