@article{ETD, recid = {7588}, author = {Khoo, Vi V.}, title = {Secondary analyses of dietary data from PRISM clinical trials to evaluate safety and efficacy of pegvaliase for adults with PKU}, publisher = {Oregon Health and Science University}, school = {M.S.}, address = {2019}, number = {ETD}, abstract = {Phenylketonuria (PKU) is a genetic disorder caused by a deficiency of phenylalanine hydroxylase leading to decreased conversion of phenylalanine (Phe) to tyrosine (Tyr). Pegvaliase™ (Palynziq™, BioMarin Pharmaceutical Inc., Novato, CA, USA), an injectable enzyme replacement therapy decreases plasma Phe by converting Phe intro trans-cinnamic acid and ammonia. This study aims to evaluate the changes in the dietary composition of participants with PKU on pegvaliase.}, url = {http://digitalcollections.ohsu.edu/record/7588}, doi = {https://doi.org/10.6083/9w0323552}, }