TY - GEN AB - Cancer is now the biggest single cause of mortality worldwide, incidence has increased by 11% in four years and cases are forecast to rise by 75% over the next 20 years [1]. Despite the huge amount of resources devoted to combating this terrible disease, progress has been slow. Most patients are still treated with painful blunt instruments like radiation and chemotherapy while new targeted treatments addressing specific genetic causes often only help a small portion of the population. Why haven't scientists and doctors been able to do more? Because each patient is different, each cancer is unique and we lack the framework for collecting, processing and understanding the mountain of information that we can generate on cancers, treatments and responses. AU - Lazar, Nathan H. DA - 2017 DO - 10.6083/m40k2833 DO - DOI ID - 7596 KW - Computational Biology KW - Cell Line KW - Machine Learning KW - Cellular Microenvironment KW - cancer L1 - https://digitalcollections.ohsu.edu/record/7596/files/Lazar.Nathan.2017.pdf L2 - https://digitalcollections.ohsu.edu/record/7596/files/Lazar.Nathan.2017.pdf L4 - https://digitalcollections.ohsu.edu/record/7596/files/Lazar.Nathan.2017.pdf LK - https://digitalcollections.ohsu.edu/record/7596/files/Lazar.Nathan.2017.pdf N2 - Cancer is now the biggest single cause of mortality worldwide, incidence has increased by 11% in four years and cases are forecast to rise by 75% over the next 20 years [1]. Despite the huge amount of resources devoted to combating this terrible disease, progress has been slow. Most patients are still treated with painful blunt instruments like radiation and chemotherapy while new targeted treatments addressing specific genetic causes often only help a small portion of the population. Why haven't scientists and doctors been able to do more? Because each patient is different, each cancer is unique and we lack the framework for collecting, processing and understanding the mountain of information that we can generate on cancers, treatments and responses. PB - Oregon Health and Science University PY - 2017 T1 - A bayesian tensor factorization algorithm to predict drug response in cancer cell lines TI - A bayesian tensor factorization algorithm to predict drug response in cancer cell lines UR - https://digitalcollections.ohsu.edu/record/7596/files/Lazar.Nathan.2017.pdf Y1 - 2017 ER -