000007601 001__ 7601
000007601 005__ 20240124114247.0
000007601 0247_ $$2DOI$$a10.6083/m44q7tj2
000007601 037__ $$aETD
000007601 245__ $$aImpact of high-complex-carbohydrate and low-carbohydrate diets and resulting body mass loss on circulating acylcarnitine concentrations in healthy adults with overweight and obesity
000007601 260__ $$bOregon Health and Science University
000007601 269__ $$a2017
000007601 336__ $$aThesis
000007601 502__ $$bM.S.
000007601 520__ $$aObesity is a public health concern with rising incidence and prevalence rates. Research exploring the metabolomic biomarkers for obesity suggests a potential association between elevated acylcarnitine concentrations in individuals with obesity compared to lean controls. Low-carbohydrate (LC) and high-complex-carbohydrate (HCC) dietary patterns are commonly followed by individuals with overweight and obesity seeking to lose weight. Yet, little is known about how these diets affect circulating acylcarnitine concentrations in combination with changes in body mass, lean mass, and fat mass.  
The goal of this secondary analysis of data obtained from the Comparison of Health Benefits and Risks of High-Carbohydrate, Low-Fat or Very-Low-Carbohydrate Diets for Weight Loss Study was to determine the effect of LC and HCC dietary interventions on circulating acylcarnitine concentrations among healthy adults with overweight and obesity. The first aim was to describe the impact of consuming a LC or HCC diet on fasting acylcarnitine concentrations at baseline and 2, 4, 6, and 18-weeks after dietary intervention. The second aim was to define the relationships between changes in lean mass, fat mass, and fasting acylcarnitine concentrations within and between the ad libitum LC diet group and the energy-matched HCC diet group.
000007601 650__ $$aCarnitine$$016164
000007601 650__ $$aObesity$$023118
000007601 650__ $$aBody Composition$$015696
000007601 650__ $$aWeight Loss$$028407
000007601 6531_ $$alow carbohydrate diet
000007601 6531_ $$afat restricted diet
000007601 691__ $$aSchool of Medicine$$041369
000007601 7001_ $$aAttema, Kathryn J.
000007601 8564_ $$91892795e-9693-4598-85cf-2eb12fc8a6bc$$s6082832$$uhttps://digitalcollections.ohsu.edu/record/7601/files/Attema.Kathryn.2017.pdf
000007601 905__ $$a/rest/prod/6w/92/4c/28/6w924c28v
000007601 909CO $$ooai:digitalcollections.ohsu.edu:7601$$pstudent-work
000007601 980__ $$aTheses and Dissertations