000007618 001__ 7618
000007618 005__ 20231129124933.0
000007618 0247_ $$2DOI$$a10.6083/m4bv7g57
000007618 037__ $$aETD
000007618 245__ $$aIdentifying risk factors for cystic fibrosis related diabetes
000007618 260__ $$bOregon Health and Science University
000007618 269__ $$a2017
000007618 336__ $$aThesis
000007618 502__ $$bM.S.
000007618 520__ $$aAs individuals with Cystic Fibrosis (CF) live longer, they can develop complications such as Cystic Fibrosis Related Diabetes (CFRD), the most common complication seen in adults with CF. Those who develop CFRD experience accelerated decline in pulmonary function and higher rates of early mortality than those without CFRD, suggesting that CFRD is a sentinel event in that person's life. Recent evidence suggests that early recognition of CFRD and tight blood glucose control mitigates some negative impacts on health. Limited research describes risk factors that predict the development of CFRD. Proposed risk factors include use of a gastrostomy tube (g-tube) for enteral feeding, low body mass index (BMI) and lower pulmonary function. The goal of this study was to determine clinical characteristics that predict the development of impaired glucose tolerance (IGT) or CFRD among children and adolescents with CF. We anticipated that regular use of a g-tube for enteral feeding, decline in pulmonary function and decline in BMI z-scores would be associated with development of IGT and/or CFRD among children and adolescents with CF.
000007618 650__ $$aCystic Fibrosis $$017315
000007618 650__ $$aRisk Factors $$025522
000007618 650__ $$aPediatrics $$023687
000007618 650__ $$a Adolescent$$014285
000007618 650__ $$aChild$$016462
000007618 650__ $$aDiabetes Mellitus $$017671
000007618 650__ $$aGastrostomy $$019425
000007618 691__ $$aSchool of Medicine$$041369
000007618 7001_ $$aSomohano, Jessica
000007618 8564_ $$9021631c0-2969-465d-bae8-1fc52918e423$$s1381804$$uhttps://digitalcollections.ohsu.edu/record/7618/files/Somohano.Jessica.2017.pdf
000007618 905__ $$a/rest/prod/1v/53/jx/49/1v53jx49g
000007618 909CO $$ooai:digitalcollections.ohsu.edu:7618$$pstudent-work
000007618 980__ $$aTheses and Dissertations