000007635 001__ 7635
000007635 005__ 20231129124932.0
000007635 0247_ $$2DOI$$a10.6083/m4gf0t11
000007635 037__ $$aETD
000007635 245__ $$aAstrocytic modulation of excitatory neuronal signaling in a mouse model of rett syndrome
000007635 260__ $$bOregon Health and Science University
000007635 269__ $$a2017
000007635 336__ $$aThesis
000007635 502__ $$bM.S.
000007635 520__ $$aAstrocyte-mediated processes are important for maintaining neuronal homeostasis and proper synaptic transmission. Recent work from the Mandel lab has implicated astrocytes in the X-chromosome linked autism-like spectrum disorder Rett syndrome (RTT), where global mutations in the methyl DNA-binding protein MeCP2 result in dysregulation of neuronal processes and severe mental retardation.
000007635 650__ $$aRett Syndrome $$028468
000007635 650__ $$aAstrocytes$$015172
000007635 650__ $$aNeurons$$022858
000007635 691__ $$aSchool of Medicine$$041369
000007635 7001_ $$aRakela, Benjamin
000007635 8564_ $$91050ac0e-9d0a-4915-8a7f-f594c83754bb$$s6034042$$uhttps://digitalcollections.ohsu.edu/record/7635/files/Rakela.Benjamin.2017.pdf
000007635 905__ $$a/rest/prod/73/66/65/03/73666503s
000007635 909CO $$ooai:digitalcollections.ohsu.edu:7635$$pstudent-work
000007635 980__ $$aTheses and Dissertations