000007666 001__ 7666
000007666 005__ 20240124114249.0
000007666 0247_ $$2DOI$$a10.6083/m4sx6csd
000007666 037__ $$aETD
000007666 245__ $$aDengue virus and the suppression of the cellular innate immune response: antiviral microRNAs as a tool for probing host-virus interactions
000007666 260__ $$bOregon Health and Science University
000007666 269__ $$a2017
000007666 336__ $$aDissertation
000007666 502__ $$bPh.D.
000007666 520__ $$aThis dissertation describes the implementation of a technique for using cellular miRNAs as tools for the discovery of virus-host interactions. With this methodology, I discovered a new function for the UPR during DENV2, namely inhibition of innate immune signaling, as well as identifying a miRNA that impedes flavivirus infection in spite of failure to enhance cellular immunity.
000007666 542__ $$fIn copyright - single owner
000007666 650__ $$aUnfolded Protein Response$$038723
000007666 650__ $$aFlavivirus$$019087
000007666 650__ $$aMicroRNAs$$034671
000007666 650__ $$aDengue Virus$$017471
000007666 6531_ $$ainnate immunity
000007666 691__ $$aSchool of Medicine$$041369
000007666 692__ $$aDepartment of Molecular Microbiology and Immunology$$041429
000007666 7001_ $$aMurphy, Ashleigh R.
000007666 8564_ $$964fef463-788f-412b-beb5-a22af51628a4$$s13936138$$uhttps://digitalcollections.ohsu.edu/record/7666/files/Murphy.Ashleigh.2017.pdf
000007666 905__ $$a/rest/prod/kw/52/j8/61/kw52j8619
000007666 909CO $$ooai:digitalcollections.ohsu.edu:7666$$pstudent-work
000007666 980__ $$aTheses and Dissertations