TY  - GEN
N2  - Alzheimer's disease (AD) is an irreversible neurodegenerative disorder.  It is the sixth leading cause of death in the United States. Genome-wide association studies have uncovered nearly 40 common genetic variants (minor allele frequency (MAF) > 5%) which are associated with increased susceptibility to AD. However, the common variants found so far do not completely account for the genetic component of the disease. With the technological advancement of deep sequencing, the focus has shifted to exploring the role of rare (MAF < 0.5%) and private variants.
DO  - 10.6083/m4tq60n9
DO  - DOI
AB  - Alzheimer's disease (AD) is an irreversible neurodegenerative disorder.  It is the sixth leading cause of death in the United States. Genome-wide association studies have uncovered nearly 40 common genetic variants (minor allele frequency (MAF) > 5%) which are associated with increased susceptibility to AD. However, the common variants found so far do not completely account for the genetic component of the disease. With the technological advancement of deep sequencing, the focus has shifted to exploring the role of rare (MAF < 0.5%) and private variants.
AD  - Oregon Health and Science University
T1  - Aggregating common, rare, and private variants in Alzheimer's disease genes
DA  - 2017
AU  - Das, Prerna
L1  - https://digitalcollections.ohsu.edu/record/7668/files/Das.Prerna.2017.pdf
PB  - Oregon Health and Science University
PY  - 2017
ID  - 7668
L4  - https://digitalcollections.ohsu.edu/record/7668/files/Das.Prerna.2017.pdf
KW  - Genome-Wide Association Study
KW  - Phenotype
KW  - Alzheimer Disease
KW  - Linkage Disequilibrium
TI  - Aggregating common, rare, and private variants in Alzheimer's disease genes
Y1  - 2017
L2  - https://digitalcollections.ohsu.edu/record/7668/files/Das.Prerna.2017.pdf
LK  - https://digitalcollections.ohsu.edu/record/7668/files/Das.Prerna.2017.pdf
UR  - https://digitalcollections.ohsu.edu/record/7668/files/Das.Prerna.2017.pdf
ER  -