000007675 001__ 7675 000007675 005__ 20240124114249.0 000007675 0247_ $$2DOI$$a10.6083/m4w66k99 000007675 037__ $$aETD 000007675 245__ $$aGrowth and carnitine status of children treated with the ketogenic diet for intractable epilepsy 000007675 260__ $$bOregon Health and Science University 000007675 269__ $$a2017 000007675 336__ $$aThesis 000007675 502__ $$bM.S. 000007675 520__ $$aLong-term treatment with the Ketogenic Diet among children with intractable epilepsy may negatively impact growth, especially linear growth, body composition, and plasma carnitine concentrations. Treatment with the Ketogenic Diet also results in an increased demand for carnitine, which may lead to hypocarnitinemia. As 90% of carnitine is stored in the muscle, the amount of muscle mass in children prior to starting dietary treatment may play a role in the carnitine status of these children. Limited research exists describing the potential relationship between, and potential protective effect of, greater muscle mass and changes in carnitine status in patients treated with the Ketogenic Diet. 000007675 650__ $$aCarnitine $$016164 000007675 650__ $$aDrug Resistant Epilepsy $$011358 000007675 650__ $$a Seizures$$025832 000007675 650__ $$aBody Composition$$015696 000007675 6531_ $$aketogenic diet 000007675 691__ $$aSchool of Medicine$$041369 000007675 7001_ $$aGavi, Natalie A. 000007675 8564_ $$962635a43-d112-47b2-8e34-e60a95c9305a$$s1982656$$uhttps://digitalcollections.ohsu.edu/record/7675/files/Gavi.Natalie.2017.pdf 000007675 905__ $$a/rest/prod/ft/84/8r/18/ft848r18v 000007675 909CO $$ooai:digitalcollections.ohsu.edu:7675$$pstudent-work 000007675 980__ $$aTheses and Dissertations