@article{ETD,
      school = {Ph.D.},
      author = {Jenkins, Chelsea},
      url = {http://digitalcollections.ohsu.edu/record/7676},
      title = {Synthetic lethality of TNK2 inhibition in PTPN11-mutant  leukemia},
      publisher = {Oregon Health and Science University},
      abstract = {This dissertation presents novel evidence that PTPN11 is  activated by an upstream kinase, TNK2. PTPN11-mutant JMML  and AML primary patient cells have displayed significant  sensitivity to TNK2 inhibition by dasatinib. My research  has revealed that PTPN11 and TNK2 interact directly,  allowing for TNK2 dependent phosphorylation of PTPN11.},
      number = {ETD},
      doi = {https://doi.org/10.6083/m4wd404b},
      recid = {7676},
      address = {2017},
}