TY - THES N2 - The human immune system’s relationship with cancer is incredibly complex. However, suggestions that the immune system can treat cancer have kept scientists searching for potential ways to augment immunity for over 100 years. We hypothesize that overcoming immune tolerance and activating a functional anti-tumor T cell response in cancer patients requires sufficient antigenic targets, tumor-specific primed T cells, the proper costimulatory signals, and the right cytokine milieu. DO - 10.6083/m42v2f7b DO - DOI AB - The human immune system’s relationship with cancer is incredibly complex. However, suggestions that the immune system can treat cancer have kept scientists searching for potential ways to augment immunity for over 100 years. We hypothesize that overcoming immune tolerance and activating a functional anti-tumor T cell response in cancer patients requires sufficient antigenic targets, tumor-specific primed T cells, the proper costimulatory signals, and the right cytokine milieu. T1 - Augmenting combination immunotherapies with vaccination or costimulatory/inhibitory antibodies for the treatment of cancer DA - 2016 AU - Messenheimer, David J. L1 - https://digitalcollections.ohsu.edu/record/7685/files/Messenheimer.David.2016.pdf PB - Marylhurst University: Oregon Health and Science University PY - 2016 ID - 7685 L4 - https://digitalcollections.ohsu.edu/record/7685/files/Messenheimer.David.2016.pdf KW - Immunotherapy KW - Antibodies KW - Vaccines KW - Neoplasms TI - Augmenting combination immunotherapies with vaccination or costimulatory/inhibitory antibodies for the treatment of cancer Y1 - 2016 L2 - https://digitalcollections.ohsu.edu/record/7685/files/Messenheimer.David.2016.pdf LK - https://digitalcollections.ohsu.edu/record/7685/files/Messenheimer.David.2016.pdf UR - https://digitalcollections.ohsu.edu/record/7685/files/Messenheimer.David.2016.pdf ER -