000007717 001__ 7717
000007717 005__ 20240124114250.0
000007717 0247_ $$2DOI$$a10.6083/pr76f396f
000007717 037__ $$aETD
000007717 245__ $$aEvidence to support antibiotic stewardship: evaluating current strategies for benchmarking antibiotic use in the hospital setting
000007717 260__ $$bMarylhurst University: Oregon Health and Science University
000007717 269__ $$a2019
000007717 336__ $$aDissertation
000007717 502__ $$bPh.D.
000007717 520__ $$aIn 2015, the Centers for Disease Control and Prevention developed the Standardized Antimicrobial Administration Ratio (SAAR) to account for underlying differences in patient characteristics that differ between facilities and increase antibiotic use. Although significant effort went into the development of the SAAR metric, several aspects required scientific advancement: 1) the models were not externally validated, 2) SAAR risk-adjusts only for facility-level characteristics, meaning the validity and utility may be sub-optimal, and 3) there are no data to support that risk-adjusted antibiotic use rates are correlated with appropriate antibiotic use. In this dissertation, my objective was to validate and refine current antibiotic utilization metrics to better support stewardship efforts in the hospital.
000007717 542__ $$fIn copyright - single owner
000007717 650__ $$aDrug Resistance$$018079
000007717 650__ $$aBacterial Infections$$015328
000007717 650__ $$aAntimicrobial Stewardship$$012178
000007717 650__ $$aEpidemiology$$018518
000007717 650__ $$aAnti-Bacterial Agents$$014846
000007717 6531_ $$arisk-adjustment
000007717 6531_ $$amicrobial
000007717 691__ $$aOHSU-PSU School of Public Health$$041366
000007717 7001_ $$aHolmer, Haley K.
000007717 8564_ $$98bc7cdd3-3706-4e9c-8c87-06634418b924$$s1900940$$uhttps://digitalcollections.ohsu.edu/record/7717/files/Holmer.Haley.2019.pdf
000007717 905__ $$a/rest/prod/pr/76/f3/96/pr76f396f
000007717 909CO $$ooai:digitalcollections.ohsu.edu:7717$$pstudent-work
000007717 980__ $$aTheses and Dissertations
000007717 980__ $$aDual Author Affiliations Cleanup