000000775 001__ 775
000000775 005__ 20260112151905.0
000000775 0247_ $$2DOI$$a10.6083/M4G73BQ8
000000775 037__ $$aETD
000000775 245__ $$aThe chemical biology of siderophores from the bacterial endosymbiots of shipworms
000000775 260__ $$bOregon Health and Science University
000000775 269__ $$a2011
000000775 336__ $$aDissertation
000000775 502__ $$bPh.D.
000000775 502__ $$gEnvironmental Science and Engineering
000000775 520__ $$aShipworms (Teredinidae) rely on gill-associated bacterial endosymbionts for wood digestion and nitrogen fixation. This study investigates iron acquisition strategies in these symbionts, focusing on siderophore production. Teredinibacter turnerae was found to synthesize a novel catecholate siderophore, turnerbactin, and its biosynthetic pathway was characterized. Mass spectrometry and genomic analyses revealed widespread siderophore potential among symbionts, predominantly catecholate types. Functional assays indicate siderophores may mediate competitive interactions rather than cooperative iron acquisition within the symbiotic community. These findings highlight siderophores as key factors in symbiont ecology and suggest roles in nutrient acquisition and microbial dynamics.
000000775 540__ $$fCC BY
000000775 542__ $$fIn copyright - single owner
000000775 650__ $$aSymbiosis$$026695
000000775 650__ $$aMarine Biology$$021842
000000775 650__ $$aSiderophores$$029823
000000775 650__ $$aWood$$027990
000000775 650__ $$aDigestion$$017807
000000775 6531_ $$ashipworms
000000775 691__ $$aSchool of Medicine$$041369
000000775 692__ $$aDepartment of Environmental and Biomolecular Systems$$041414
000000775 7001_ $$aHan, Andrew$$uOregon Health and Science University$$041354
000000775 7201_ $$aHaygood, Margo$$uOregon Health and Science University$$041354$$7Personal$$eAdvisor
000000775 8564_ $$982b8493d-fd6e-4c4b-9b32-61cd1c9349d4$$s3194985$$uhttps://digitalcollections.ohsu.edu/record/775/files/778_etd.pdf$$ePublic$$293a8407dd27d2f87eb6212eead7b9b3f$$31
000000775 905__ $$a/rest/prod/r7/81/wg/00/r781wg00k
000000775 909CO $$ooai:digitalcollections.ohsu.edu:775$$pstudent-work
000000775 980__ $$aTheses and Dissertations