000007848 001__ 7848 000007848 005__ 20251028134807.0 000007848 0247_ $$2DOI$$a10.6083/M44J0D67 000007848 037__ $$aETD 000007848 245__ $$aDevelopment & use of site-directed labeling methods to study the structure, dynamics, and interactions of GPCRs with their affiliate proteins arrestin and rhodopsin kinase 000007848 260__ $$bOregon Health and Science University 000007848 269__ $$a2016 000007848 336__ $$aDissertation 000007848 502__ $$bPh.D. 000007848 520__ $$aThis dissertation describes my work on two main projects, first to expand and calibrate a site-directed fluorescence labeling method that can assess distance relationships between discrete sites within or between two proteins, and second to study the interactions of rhodopsin kinase with its substrate, rhodopsin. 000007848 542__ $$fIn copyright - single owner 000007848 650__ $$aG-Protein-Coupled Receptor Kinases$$038019 000007848 650__ $$aRhodopsin$$025463 000007848 650__ $$aSpectrometry, Fluorescence$$026216 000007848 650__ $$aReceptors, G-Protein-Coupled$$035314 000007848 6531_ $$aprotein dynamics 000007848 691__ $$aSchool of Medicine$$041369 000007848 692__ $$aDepartment of Biochemistry and Molecular Biology$$041396 000007848 7001_ $$aBrunette, Amber$$uOregon Health and Science University$$041354 000007848 7201_ $$aFarrens, David$$uOregon Health and Science University$$041354$$7Personal$$eAdvisor$$eMentor 000007848 8564_ $$969b17043-cbad-4d91-9d1d-26c14dfcee53$$s7843004$$uhttps://digitalcollections.ohsu.edu/record/7848/files/Brunette.Amber.M.Jones.2016.pdf$$ePublic$$29ebac35eac56e0c10cb16cd4a187fce7$$31 000007848 905__ $$a/rest/prod/54/25/kb/29/5425kb299 000007848 909CO $$ooai:digitalcollections.ohsu.edu:7848$$pstudent-work 000007848 980__ $$aTheses and Dissertations