000007856 001__ 7856
000007856 005__ 20251113123819.0
000007856 0247_ $$2DOI$$a10.6083/M4C53JVX
000007856 037__ $$aETD
000007856 245__ $$aComplex regulation of Olig2 activity during spinal cord development
000007856 260__ $$bOregon Health and Science University
000007856 269__ $$a2015
000007856 336__ $$aDissertation
000007856 502__ $$bPh.D.
000007856 502__ $$gNeuroscience
000007856 520__ $$aThe transcription factor Olig2 is essential for the specification of neurons and  oligodendrocytes, as well as a subset of astrocytes during both neural tube and telencephalon  development. Yet, how this single transcription factor is capable of generating these disparate cell  types has remained largely unknown. This work elucidates multiple mechanisms, including temporal  phosphorylation and dimerization partner choice, which govern the developmental action of Olig2.
000007856 542__ $$fIn copyright - single owner
000007856 650__ $$aSpinal Cord$$026279
000007856 650__ $$aAstrocytes$$015172
000007856 650__ $$aTranscription Factors
000007856 691__ $$aSchool of Medicine$$041369
000007856 692__ $$aVollum Institute$$041509
000007856 7001_ $$aHarrold, Alexandria$$uOregon Health and Science University$$041354
000007856 7201_ $$aLee, Soo-Kyung$$uOregon Health and Science University$$041354$$7Personal$$eMentor
000007856 8564_ $$9dd6eba9b-c8d4-4b5a-940d-13aaf6f60873$$s18907612$$uhttps://digitalcollections.ohsu.edu/record/7856/files/Harrold.Alexandria.2015.pdf$$ePublic$$244e4952f865fdcf098d3b07af6eb8877$$31
000007856 905__ $$a/rest/prod/dr/26/xx/92/dr26xx92x
000007856 909CO $$ooai:digitalcollections.ohsu.edu:7856$$pstudent-work
000007856 980__ $$aTheses and Dissertations