TY - GEN N2 - The importance of understanding sex differences in patients with clinical pain has spurred investigations of real and potential sex differences in pain transmission and modulation. In pre-clinical and rodent models, differences in basal pain thresholds or sensitivity have been identified with multiple stimuli but these results are often inconsistent, and frequently confounded by test conditions. Although female and male rodents commonly display similar pain thresholds, observed differences in the development, response to and resolution of persistent pain suggest that sex differences may arise in endogenous pain modulation. DO - 10.6083/c534fp47v DO - DOI AB - The importance of understanding sex differences in patients with clinical pain has spurred investigations of real and potential sex differences in pain transmission and modulation. In pre-clinical and rodent models, differences in basal pain thresholds or sensitivity have been identified with multiple stimuli but these results are often inconsistent, and frequently confounded by test conditions. Although female and male rodents commonly display similar pain thresholds, observed differences in the development, response to and resolution of persistent pain suggest that sex differences may arise in endogenous pain modulation. T1 - Rostral ventromedial medulla (RVM) pain modulating neurons in male and female rats with persistent pain DA - 2020 AU - Hanson, Erica L1 - https://digitalcollections.ohsu.edu/record/8037/files/Hanson.Erica.2020.pdf PB - Oregon Health and Science University PY - 2020 ID - 8037 L4 - https://digitalcollections.ohsu.edu/record/8037/files/Hanson.Erica.2020.pdf KW - Brain Stem KW - Chronic Pain KW - Rodentia KW - sex differences KW - pain thresholds KW - rostral ventromedial medulla TI - Rostral ventromedial medulla (RVM) pain modulating neurons in male and female rats with persistent pain Y1 - 2020 L2 - https://digitalcollections.ohsu.edu/record/8037/files/Hanson.Erica.2020.pdf LK - https://digitalcollections.ohsu.edu/record/8037/files/Hanson.Erica.2020.pdf UR - https://digitalcollections.ohsu.edu/record/8037/files/Hanson.Erica.2020.pdf ER -