000008037 001__ 8037 000008037 005__ 20240124114257.0 000008037 0247_ $$2DOI$$a10.6083/c534fp47v 000008037 037__ $$aETD 000008037 245__ $$aRostral ventromedial medulla (RVM) pain modulating neurons in male and female rats with persistent pain 000008037 260__ $$bOregon Health and Science University 000008037 269__ $$a2020 000008037 336__ $$aDissertation 000008037 502__ $$bPh.D. 000008037 520__ $$aThe importance of understanding sex differences in patients with clinical pain has spurred investigations of real and potential sex differences in pain transmission and modulation. In pre-clinical and rodent models, differences in basal pain thresholds or sensitivity have been identified with multiple stimuli but these results are often inconsistent, and frequently confounded by test conditions. Although female and male rodents commonly display similar pain thresholds, observed differences in the development, response to and resolution of persistent pain suggest that sex differences may arise in endogenous pain modulation. 000008037 542__ $$fIn copyright - single owner 000008037 650__ $$aBrain Stem$$015800 000008037 650__ $$aChronic Pain$$039552 000008037 650__ $$aRodentia$$025590 000008037 6531_ $$asex differences 000008037 6531_ $$apain thresholds 000008037 6531_ $$arostral ventromedial medulla 000008037 691__ $$aSchool of Medicine$$041369 000008037 692__ $$aVollum Institute$$041509 000008037 7001_ $$aHanson, Erica 000008037 8564_ $$98f60c0cc-87c2-4dc4-bfae-91b92531845c$$s2888249$$uhttps://digitalcollections.ohsu.edu/record/8037/files/Hanson.Erica.2020.pdf 000008037 905__ $$a/rest/prod/c5/34/fp/47/c534fp47v 000008037 909CO $$ooai:digitalcollections.ohsu.edu:8037$$pstudent-work 000008037 980__ $$aTheses and Dissertations