000008043 001__ 8043
000008043 005__ 20240124114257.0
000008043 0247_ $$2DOI$$a10.6083/w3763753n
000008043 037__ $$aETD
000008043 245__ $$aValidation of an image analysis algorithm for quantifying CD138 immunohistochemical marker in  plasma cell neoplasms
000008043 260__ $$bOregon Health and Science University
000008043 269__ $$a2020
000008043 336__ $$aCapstone
000008043 502__ $$bM.S.
000008043 520__ $$aPlasma cell neoplasms are a spectrum of disorders caused by the proliferation of monoclonal plasma cells in the bone marrow leading to the production of monoclonal immunoglobulin. Included in this spectrum, from least severe to most severe, are monoclonal gammopathy of undetermined significance, smoldering multiple myeloma, and plasma cell myeloma. Each diagnosis carries a different prognosis and requires different clinical management. For example, the median overall survival of patients with Stage I, II, and III PCM has been shown to be 62, 44, and 29 months, respectively, while the median overall survival of patients with monoclonal gammopathy of undetermined significance is expected to be only slightly shorter than that of age-matched controls.1-4 Thus, making the correct diagnosis amongst this spectrum of disorders is paramount for the prognostication and proper clinical management of plasma cell neoplasms.
000008043 650__ $$aBone Marrow$$015725
000008043 650__ $$aAlgorithms$$014437
000008043 6531_ $$acomputer assisted image analysis
000008043 6531_ $$aplasma cell neoplasms
000008043 6531_ $$acd138 antigen
000008043 691__ $$aSchool of Medicine$$041369
000008043 692__ $$aDepartment of Medical Informatics and Clinical Epidemiology$$041422
000008043 7001_ $$aNgoc, Tran$$uOregon Health and Science University$$041354
000008043 8564_ $$9ff97c992-17d2-4d13-a189-e1c25f145bc7$$s2029387$$uhttps://digitalcollections.ohsu.edu/record/8043/files/Ngoc.Tran.2020.pdf
000008043 905__ $$a/rest/prod/w3/76/37/53/w3763753n
000008043 909CO $$ooai:digitalcollections.ohsu.edu:8043$$pstudent-work
000008043 980__ $$aTheses and Dissertations