@article{ETD, recid = {8049}, author = {Leary, Celeste I.}, title = {Linear system analysis for photon-counting computed tomography protocol optimization}, publisher = {Oregon Health and Science University}, school = {Ph.D.}, address = {2020}, number = {ETD}, abstract = {Contrast-enhanced computed tomography (CT) has found widespread use as a diagnostic imaging tool, with contrast used in approximately 60% of all CT scans. Dual-Energy CT (DECT) offers improvements to standard CT contrast imaging, particularly through material differentiation which improves diagnostic criteria and makes virtual non-contrast imaging possible. Photon-Counting CT (PCCT) improves upon DECT with the use of multiple adjustable energy-thresholds. This technology promises better material differentiation, multi-contrast imaging, increased CNR, reduced dose for maintained image quality, and material-specific K-edge imaging, but optimization of PCCT protocols is needed in order to maximize these benefits.}, url = {http://digitalcollections.ohsu.edu/record/8049}, doi = {https://doi.org/10.6083/qb98mg038}, }