TY - GEN N2 - Contrast-enhanced computed tomography (CT) has found widespread use as a diagnostic imaging tool, with contrast used in approximately 60% of all CT scans. Dual-Energy CT (DECT) offers improvements to standard CT contrast imaging, particularly through material differentiation which improves diagnostic criteria and makes virtual non-contrast imaging possible. Photon-Counting CT (PCCT) improves upon DECT with the use of multiple adjustable energy-thresholds. This technology promises better material differentiation, multi-contrast imaging, increased CNR, reduced dose for maintained image quality, and material-specific K-edge imaging, but optimization of PCCT protocols is needed in order to maximize these benefits. DO - 10.6083/qb98mg038 DO - DOI AB - Contrast-enhanced computed tomography (CT) has found widespread use as a diagnostic imaging tool, with contrast used in approximately 60% of all CT scans. Dual-Energy CT (DECT) offers improvements to standard CT contrast imaging, particularly through material differentiation which improves diagnostic criteria and makes virtual non-contrast imaging possible. Photon-Counting CT (PCCT) improves upon DECT with the use of multiple adjustable energy-thresholds. This technology promises better material differentiation, multi-contrast imaging, increased CNR, reduced dose for maintained image quality, and material-specific K-edge imaging, but optimization of PCCT protocols is needed in order to maximize these benefits. T1 - Linear system analysis for photon-counting computed tomography protocol optimization DA - 2020 AU - Leary, Celeste I. L1 - https://digitalcollections.ohsu.edu/record/8049/files/Leary.Celeste.2020.pdf PB - Oregon Health and Science University PY - 2020 ID - 8049 L4 - https://digitalcollections.ohsu.edu/record/8049/files/Leary.Celeste.2020.pdf KW - transmission computed tomography TI - Linear system analysis for photon-counting computed tomography protocol optimization Y1 - 2020 L2 - https://digitalcollections.ohsu.edu/record/8049/files/Leary.Celeste.2020.pdf LK - https://digitalcollections.ohsu.edu/record/8049/files/Leary.Celeste.2020.pdf UR - https://digitalcollections.ohsu.edu/record/8049/files/Leary.Celeste.2020.pdf ER -