@article{ETD, school = {Ph.D.}, author = {Zebertavage, Lauren K.}, url = {http://digitalcollections.ohsu.edu/record/8063}, title = {The role of radiation therapy in generating effective anti-tumor CD8+ T cell responses}, publisher = {Oregon Health and Science University}, abstract = {Effective treatments for cancer have traditionally been divided into three separate arms: surgery, chemotherapy, and radiotherapy. Recently, however, a fourth arm, known as cancer immunotherapy, has been incorporated into treatment regimens and clinical trials with remarkable efficacy. These immunotherapies, designed to generate anticancer immune responses, have emphasized the importance of the immune system in controlling cancer and have placed greater focus on the the immune consequences of more traditional therapies. In this thesis, we have attempted to elucidate the way that radiotherapy can stimulate the interactions between the immune system, specifically CD8+ T cells, and cancer cells to induce lasting clearance of tumors.}, number = {ETD}, doi = {https://doi.org/10.6083/g732d957m}, recid = {8063}, address = {2020}, }