TY  - GEN
N2  - Effective treatments for cancer have traditionally been divided into three separate arms: surgery, chemotherapy, and radiotherapy. Recently, however, a fourth arm, known as cancer immunotherapy, has been incorporated into treatment regimens and clinical trials with remarkable efficacy. These immunotherapies, designed to generate anticancer immune responses, have emphasized the importance of the immune system in controlling cancer and have placed greater focus on the the immune consequences of more traditional therapies. In this thesis, we have attempted to elucidate the way that radiotherapy can stimulate the interactions between the immune system, specifically CD8+ T cells, and cancer cells to induce lasting clearance of tumors.
DO  - 10.6083/g732d957m
DO  - DOI
AB  - Effective treatments for cancer have traditionally been divided into three separate arms: surgery, chemotherapy, and radiotherapy. Recently, however, a fourth arm, known as cancer immunotherapy, has been incorporated into treatment regimens and clinical trials with remarkable efficacy. These immunotherapies, designed to generate anticancer immune responses, have emphasized the importance of the immune system in controlling cancer and have placed greater focus on the the immune consequences of more traditional therapies. In this thesis, we have attempted to elucidate the way that radiotherapy can stimulate the interactions between the immune system, specifically CD8+ T cells, and cancer cells to induce lasting clearance of tumors.
T1  - The role of radiation therapy in generating effective anti-tumor CD8+ T cell responses
DA  - 2020
AU  - Zebertavage, Lauren K.
L1  - https://digitalcollections.ohsu.edu/record/8063/files/Zebertavage.Lauren.2020.pdf
PB  - Oregon Health and Science University
PY  - 2020
ID  - 8063
L4  - https://digitalcollections.ohsu.edu/record/8063/files/Zebertavage.Lauren.2020.pdf
KW  - Immunotherapy
KW  - Radiation
KW  - natural killer t cell
KW  - mhc i molecules
KW  - cancer
TI  - The role of radiation therapy in generating effective anti-tumor CD8+ T cell responses
Y1  - 2020
L2  - https://digitalcollections.ohsu.edu/record/8063/files/Zebertavage.Lauren.2020.pdf
LK  - https://digitalcollections.ohsu.edu/record/8063/files/Zebertavage.Lauren.2020.pdf
UR  - https://digitalcollections.ohsu.edu/record/8063/files/Zebertavage.Lauren.2020.pdf
ER  -