TY  - GEN
N2  - The ability of tumors to induce immunosuppression and inhibit the cytolytic function of tumor-infiltrating lymphocytes (TIL) is a major obstacle to creating effective immunotherapies for cancer patients. The levels of galectin-3 (Gal-3) protein, which contribute to the immunosuppression, are increased during tumor progression in many cancers. Gal-3 contributes to immunosuppression by inducing M2 (wound healing) polarization of tumor-associated macrophages and playing a role in the survival and metastasis of cancer cells.
DO  - 10.6083/j3860762v
DO  - DOI
AB  - The ability of tumors to induce immunosuppression and inhibit the cytolytic function of tumor-infiltrating lymphocytes (TIL) is a major obstacle to creating effective immunotherapies for cancer patients. The levels of galectin-3 (Gal-3) protein, which contribute to the immunosuppression, are increased during tumor progression in many cancers. Gal-3 contributes to immunosuppression by inducing M2 (wound healing) polarization of tumor-associated macrophages and playing a role in the survival and metastasis of cancer cells.
T1  - The role of intracellular Galectin-3 in the CD8 T cell response
DA  - 2020
AU  - Amani, Mohammad F.
L1  - https://digitalcollections.ohsu.edu/record/8068/files/Amani.Mohammad.2020.pdf
PB  - Oregon Health and Science University
PY  - 2020
ID  - 8068
L4  - https://digitalcollections.ohsu.edu/record/8068/files/Amani.Mohammad.2020.pdf
KW  - Galectin 3
KW  - Immunotherapy
KW  - Immunohistochemistry
KW  - cd8 positive t lymphocytes
KW  - immunology
KW  - t8 lymphocyte
TI  - The role of intracellular Galectin-3 in the CD8 T cell response
Y1  - 2020
L2  - https://digitalcollections.ohsu.edu/record/8068/files/Amani.Mohammad.2020.pdf
LK  - https://digitalcollections.ohsu.edu/record/8068/files/Amani.Mohammad.2020.pdf
UR  - https://digitalcollections.ohsu.edu/record/8068/files/Amani.Mohammad.2020.pdf
ER  -