@article{IR,
      author = {Hutchens, Michael and Matsushita, Katsuyuki and Eiwaz,  Mahaba and Saritas, Turgay and McCormick, Jim},
      url = {http://digitalcollections.ohsu.edu/record/8224},
      title = {Proximal tubule megalin inhibition prevents acute kidney  injury due to rhabdomyolysis in mice},
      publisher = {Oregon Health and Science University},
      abstract = {Destruction of skeletal muscle (rhabdomyolysis) releases  myoglobin, causing rhabdomyolysis-induced acute renal  injury (rhAKI). As rhAKI commonly occurs in austere  environments such as earthquakes and armed conflict,  supportive care is challenging. Specific therapy would be a  significant advance. Since myoglobin is taken into renal  tubular cells via the renal cortex-specific transporter  megalin (LRP2), we hypothesized that interfering with  megalin would ameliorate rhAKI.},
      number = {IR},
      doi = {https://doi.org/10.6083/ks65hc833},
      recid = {8224},
      address = {2020},
}