@article{IR, author = {Fombonne, Eric and O'Roak, Brian and Coppola, Leigh and Mastel, Sarah and Beeson, Landon}, url = {http://digitalcollections.ohsu.edu/record/8239}, title = {Psychiatric and medical profiles of autistic adults in the SPARK cohort}, publisher = {Oregon Health and Science University}, abstract = {This study examined lifetime medical and psychiatric morbidity reported by caregivers of 2,917 autistic adults participating in the US research cohort SPARK. Participants were78.4% male, 47.3% had intellectual disability, and 32.1% had persistent language impairments. Childhood language disorders (59.7%), speech/articulation problems (32.8%), sleep (39.4%) and eating problems (29.4%), motor delays (22.8%) and history of seizure (15.5%) were the most frequently reported clinical features. Over two thirds (67.2%) had been diagnosed with at least one psychiatric disorder (anxiety disorders: 41.1%; ADHD: 38.7%). Compared to verbally fluent participants, those with language impairments had lower frequencies of almost all psychiatric disorders. Female sex and older age were associated with higher medical and psychiatric morbidity.}, number = {IR}, doi = {https://doi.org/10.6083/2514nm14d}, recid = {8239}, address = {2020}, }