TY - GEN N2 - This study examined lifetime medical and psychiatric morbidity reported by caregivers of 2,917 autistic adults participating in the US research cohort SPARK. Participants were78.4% male, 47.3% had intellectual disability, and 32.1% had persistent language impairments. Childhood language disorders (59.7%), speech/articulation problems (32.8%), sleep (39.4%) and eating problems (29.4%), motor delays (22.8%) and history of seizure (15.5%) were the most frequently reported clinical features. Over two thirds (67.2%) had been diagnosed with at least one psychiatric disorder (anxiety disorders: 41.1%; ADHD: 38.7%). Compared to verbally fluent participants, those with language impairments had lower frequencies of almost all psychiatric disorders. Female sex and older age were associated with higher medical and psychiatric morbidity. DO - 10.6083/2514nm14d DO - DOI AB - This study examined lifetime medical and psychiatric morbidity reported by caregivers of 2,917 autistic adults participating in the US research cohort SPARK. Participants were78.4% male, 47.3% had intellectual disability, and 32.1% had persistent language impairments. Childhood language disorders (59.7%), speech/articulation problems (32.8%), sleep (39.4%) and eating problems (29.4%), motor delays (22.8%) and history of seizure (15.5%) were the most frequently reported clinical features. Over two thirds (67.2%) had been diagnosed with at least one psychiatric disorder (anxiety disorders: 41.1%; ADHD: 38.7%). Compared to verbally fluent participants, those with language impairments had lower frequencies of almost all psychiatric disorders. Female sex and older age were associated with higher medical and psychiatric morbidity. AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University T1 - Psychiatric and medical profiles of autistic adults in the SPARK cohort DA - 2020 AU - Fombonne, Eric AU - O'Roak, Brian AU - Coppola, Leigh AU - Mastel, Sarah AU - Beeson, Landon L1 - https://digitalcollections.ohsu.edu/record/8239/files/Eric-Fombonne.pdf PB - Oregon Health and Science University PY - 2020 ID - 8239 L4 - https://digitalcollections.ohsu.edu/record/8239/files/Eric-Fombonne.pdf KW - Autism Spectrum Disorder KW - Language Disorders KW - Intellectual Disability KW - Mental Disorders KW - Anxiety Disorders KW - Attention Deficit Disorder with Hyperactivity KW - Specific Language Disorder TI - Psychiatric and medical profiles of autistic adults in the SPARK cohort Y1 - 2020 L2 - https://digitalcollections.ohsu.edu/record/8239/files/Eric-Fombonne.pdf LK - https://digitalcollections.ohsu.edu/record/8239/files/Eric-Fombonne.pdf UR - https://digitalcollections.ohsu.edu/record/8239/files/Eric-Fombonne.pdf ER -