000008239 001__ 8239
000008239 005__ 20240415104310.0
000008239 0247_ $$2DOI$$a10.6083/2514nm14d
000008239 037__ $$aIR
000008239 245__ $$aPsychiatric and medical profiles of autistic adults in the SPARK cohort
000008239 260__ $$bOregon Health and Science University
000008239 269__ $$a2020
000008239 336__ $$aAbstract
000008239 520__ $$aThis study examined lifetime medical and psychiatric morbidity reported by caregivers of 2,917 autistic adults participating in the US research cohort SPARK. Participants were78.4% male, 47.3% had intellectual disability, and 32.1% had persistent language impairments. Childhood language disorders (59.7%), speech/articulation problems (32.8%), sleep (39.4%) and eating problems (29.4%), motor delays (22.8%) and history of seizure (15.5%) were the most frequently reported clinical features. Over two thirds (67.2%) had been diagnosed with at least one psychiatric disorder (anxiety disorders: 41.1%; ADHD: 38.7%). Compared to verbally fluent participants, those with language impairments had lower frequencies of almost all psychiatric disorders. Female sex and older age were associated with higher medical and psychiatric morbidity.
000008239 540__ $$fCC BY
000008239 542__ $$fIn copyright - joint owners
000008239 650__ $$aAutism Spectrum Disorder$$011199
000008239 650__ $$aLanguage Disorders$$021313
000008239 650__ $$aIntellectual Disability$$022050
000008239 650__ $$aMental Disorders$$015415
000008239 650__ $$aAnxiety Disorders$$014947
000008239 650__ $$aAttention Deficit Disorder with Hyperactivity$$015204
000008239 650__ $$aSpecific Language Disorder$$013177
000008239 691__ $$aSchool of Medicine$$041369
000008239 692__ $$aDepartment of Psychiatry$$041443
000008239 7001_ $$aFombonne, Eric$$uOregon Health and Science University$$041354
000008239 7001_ $$aO'Roak, Brian$$uOregon Health and Science University$$041354
000008239 7001_ $$aCoppola, Leigh$$uOregon Health and Science University$$041354
000008239 7001_ $$aMastel, Sarah$$uOregon Health and Science University$$041354
000008239 7001_ $$aBeeson, Landon$$uOregon Health and Science University$$041354
000008239 711__ $$aResearch Week$$uOregon Health and Science University$$d2020
000008239 8564_ $$9938a28aa-4d10-4fc6-b213-b9db5589aab2$$s44641$$uhttps://digitalcollections.ohsu.edu/record/8239/files/Eric-Fombonne.pdf
000008239 905__ $$a/rest/prod/25/14/nm/14/2514nm14d
000008239 980__ $$aResearch Week