TY - GEN N2 - Patterns of alcohol consumption during adolescence differ from those observed during adulthood; namely, adolescents are more likely to consume alcohol less frequently, but in larger quantities per occasion, when compared to adults. Importantly, this binge-pattern of drinking carries substantial risks for adverse outcomes, including involvement in motor vehicle accidents, alcohol poisoning, and sexual victimization. Although prior work has examined neural correlates of emergent alcohol use among adolescent populations, the present study takes a novel, data-driven approach by incorporating graph theory metrics of resting-state functional connectivity with predictive modeling via machine learning. To identify risk factors for future binge drinking, a subset of participants were selected from an ongoing prospective longitudinal study (National Consortium on Alcohol and Neurodevelopment in Adolescence). All participants were alcohol-na?ve at baseline (n=150), but 51% (n=77) emerged into binge drinking over the course of four years of follow-up assessments (transitioners), while the rest remained abstinent from alcohol use (controls). DO - 10.6083/tm70mv665 DO - DOI AB - Patterns of alcohol consumption during adolescence differ from those observed during adulthood; namely, adolescents are more likely to consume alcohol less frequently, but in larger quantities per occasion, when compared to adults. Importantly, this binge-pattern of drinking carries substantial risks for adverse outcomes, including involvement in motor vehicle accidents, alcohol poisoning, and sexual victimization. Although prior work has examined neural correlates of emergent alcohol use among adolescent populations, the present study takes a novel, data-driven approach by incorporating graph theory metrics of resting-state functional connectivity with predictive modeling via machine learning. To identify risk factors for future binge drinking, a subset of participants were selected from an ongoing prospective longitudinal study (National Consortium on Alcohol and Neurodevelopment in Adolescence). All participants were alcohol-na?ve at baseline (n=150), but 51% (n=77) emerged into binge drinking over the course of four years of follow-up assessments (transitioners), while the rest remained abstinent from alcohol use (controls). AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health & Science University, Swedish Neuroscience Institute AD - Oregon Health and Science University T1 - Predicting adolescent binge drinking from brain networks at rest DA - 2020 AU - Kliamovich, Dakota AU - Morales, Angelica AU - Harman, Gareth AU - Boyd, Stephen L1 - https://digitalcollections.ohsu.edu/record/8240/files/Dakota-Kliamovich.pdf PB - Oregon Health and Science University LA - eng PY - 2020 ID - 8240 L4 - https://digitalcollections.ohsu.edu/record/8240/files/Dakota-Kliamovich.pdf KW - Adolescent KW - Alcoholism KW - Binge Drinking KW - Magnetic Resonance Imaging KW - resting-state FMRI KW - graph theory KW - neurodevelopment TI - Predicting adolescent binge drinking from brain networks at rest Y1 - 2020 L2 - https://digitalcollections.ohsu.edu/record/8240/files/Dakota-Kliamovich.pdf LK - https://digitalcollections.ohsu.edu/record/8240/files/Dakota-Kliamovich.pdf UR - https://digitalcollections.ohsu.edu/record/8240/files/Dakota-Kliamovich.pdf ER -