000008240 001__ 8240
000008240 005__ 20240415101606.0
000008240 0247_ $$2DOI$$a10.6083/tm70mv665
000008240 037__ $$aIR
000008240 041__ $$aeng
000008240 245__ $$aPredicting adolescent binge drinking from brain networks at rest
000008240 260__ $$bOregon Health and Science University
000008240 269__ $$a2020
000008240 336__ $$aAbstract
000008240 520__ $$aPatterns of alcohol consumption during adolescence differ from those observed during adulthood; namely, adolescents are more likely to consume alcohol less frequently, but in larger quantities per occasion, when compared to adults. Importantly, this binge-pattern of drinking carries substantial risks for adverse outcomes, including involvement in motor vehicle accidents, alcohol poisoning, and sexual victimization. Although prior work has examined neural correlates of emergent alcohol use among adolescent populations, the present study takes a novel, data-driven approach by incorporating graph theory metrics of resting-state functional connectivity with predictive modeling via machine learning. To identify risk factors for future binge drinking, a subset of participants were selected from an ongoing prospective longitudinal study (National Consortium on Alcohol and Neurodevelopment in Adolescence). All participants were alcohol-na?ve at baseline (n=150), but 51% (n=77) emerged into binge drinking over the course of four years of follow-up assessments (transitioners), while the rest remained abstinent from alcohol use (controls).
000008240 540__ $$fCC BY
000008240 542__ $$fIn copyright - joint owners
000008240 650__ $$aAdolescent$$014285
000008240 650__ $$aAlcoholism$$014412
000008240 650__ $$aBinge Drinking$$040232
000008240 650__ $$aMagnetic Resonance Imaging$$021747
000008240 6531_ $$aresting-state FMRI
000008240 6531_ $$agraph theory
000008240 6531_ $$aneurodevelopment
000008240 691__ $$aSchool of Medicine$$041369
000008240 692__ $$aDepartment of Behavioral Neuroscience$$041394
000008240 7001_ $$aKliamovich, Dakota$$uOregon Health and Science University$$041354
000008240 7001_ $$aMorales, Angelica$$uOregon Health and Science University$$041354
000008240 7001_ $$aHarman, Gareth$$uOregon Health & Science University, Swedish Neuroscience Institute$$041353
000008240 7001_ $$aBoyd, Stephen$$uOregon Health and Science University$$041354
000008240 711__ $$aResearch Week$$uOregon Health and Science University$$d2020
000008240 8564_ $$9468a34b6-372d-445e-943c-6ef8908bfbab$$s48954$$uhttps://digitalcollections.ohsu.edu/record/8240/files/Dakota-Kliamovich.pdf
000008240 905__ $$a/rest/prod/tm/70/mv/66/tm70mv665
000008240 980__ $$aResearch Week