@article{IR,
      author = {Prince, Annie and Depenweiller, Maria and Chambers, Ash  and Ahring, Kirsten and Moseley, Kathryn and Kumru, Burcu},
      url = {http://digitalcollections.ohsu.edu/record/8244},
      title = {Large neutral amino acid supplementation improves clinical  efficacy of usual care in adult PKU},
      publisher = {Oregon Health and Science University},
      abstract = {PKU requires lifelong management, but the childhood PKU  diet does not accommodate for post-adolescent patient  variations, including: (1) the diet's effect on blood  phenylalanine (Phe) concentrations, and (2) the therapeutic  benefits of prescribed blood Phe targets. Most adult  patients discontinue the inflexible diet, and are exposed  to PKU's adverse effects. Research supports large neutral  amino acids (LNAAs) as potential alternative strategy; we  propose an additive LNAA strategy. We aim to evaluate the  clinical efficacy of a combined treatment strategy: usual  care (the PKU diet) with LNAA supplementation.},
      number = {IR},
      doi = {https://doi.org/10.6083/np1939959},
      recid = {8244},
      address = {2020},
}