000008257 001__ 8257 000008257 005__ 20240412095833.0 000008257 0247_ $$2DOI$$a10.6083/6108vb81z 000008257 037__ $$aIR 000008257 041__ $$aeng 000008257 245__ $$aMEG as a predictor of the epileptogenic zone in patients being evaluated for epilepsy surgery 000008257 260__ $$bOregon Health and Science University 000008257 269__ $$a2020 000008257 336__ $$aAbstract 000008257 520__ $$aMagnetoencephalography (MEG) measures cortically-generated magnetic fields and creates a map of current dipoles that is overlaid on Magnetic Resonance Imaging (MRI) images of the brain in order to predict the epileptogenic zone. It is a part of the armamentarium of diagnostic tests available in the presurgical workup in patients with pharmacoresistant focal epilepsy. Its efficacy and reliability in providing results concordant with other diagnostic studies and identifying additional epileptogenic foci is well-described in the literature. OHSU does not currently possess MEG as a diagnostic tool, requiring patients recommended for MEG evaluation to travel to out-of-state medical centers, often at significant personal cost. The study objective is to determine whether the spatial distribution of spike sources determined by MEG provides reliable information compared to intracranial electroencephalography (EEG) for planning surgery and predicting outcomes in patients with medically refractory epilepsy at OHSU. 000008257 540__ $$fCC BY 000008257 542__ $$fIn copyright - joint owners 000008257 650__ $$aDrug Resistant Epilepsy$$011358 000008257 650__ $$aEpilepsy$$018531 000008257 650__ $$aMagnetic Resonance Imaging$$021747 000008257 650__ $$aMagnetoencephalography$$028234 000008257 6531_ $$aMEG 000008257 6531_ $$apharmacoresistant epilepsy 000008257 6531_ $$amedically refractory epilepsy 000008257 6531_ $$aintracranial electroencephalography 000008257 691__ $$aSchool of Medicine$$041369 000008257 692__ $$aDepartment of Neurology$$041431 000008257 7001_ $$aEdwards, Jared$$uOregon Health and Science University$$041354 000008257 7001_ $$aStedelin, Brittany$$uOregon Health and Science University$$041354 000008257 7001_ $$aPangelinan, Kelsey$$uOregon Health and Science University$$041354 000008257 711__ $$aResearch Week$$uOregon Health and Science University$$d2020 000008257 8564_ $$918eb6a66-ac1c-4952-a780-c9eba9173f0f$$s47513$$uhttps://digitalcollections.ohsu.edu/record/8257/files/Jared-Edwards.pdf 000008257 905__ $$a/rest/prod/61/08/vb/81/6108vb81z 000008257 980__ $$aResearch Week