TY - GEN N2 - Sarcoma is a cancer arising in the bone, connective, or soft-tissue and occurs at any age. Among these, spindle cell rhabdomyosarcoma (SCR) is a rare, aggressive skeletal muscle subtype predominately noted in children. Patients with SCR have poor outcomes despite intensive chemotherapy and radiation treatments, which emphasizes the need to understand tumor biology and identify molecularly targetable treatment options. DO - 10.6083/2514nm15p DO - DOI AB - Sarcoma is a cancer arising in the bone, connective, or soft-tissue and occurs at any age. Among these, spindle cell rhabdomyosarcoma (SCR) is a rare, aggressive skeletal muscle subtype predominately noted in children. Patients with SCR have poor outcomes despite intensive chemotherapy and radiation treatments, which emphasizes the need to understand tumor biology and identify molecularly targetable treatment options. AD - Oregon Health and Science University AD - Oregon Health and Science University T1 - Investigating the therapeutic potential of molecularly targeted therapy in pediatric spindle cell rhabodmyosarcoma DA - 2020 AU - Choo, Florence AU - Davare, Monika L1 - https://digitalcollections.ohsu.edu/record/8279/files/Choo_Presentation.pdf L1 - https://digitalcollections.ohsu.edu/record/8279/files/Florence-Choo.pdf PB - Oregon Health and Science University LA - eng PY - 2020 ID - 8279 L4 - https://digitalcollections.ohsu.edu/record/8279/files/Choo_Presentation.pdf L4 - https://digitalcollections.ohsu.edu/record/8279/files/Florence-Choo.pdf KW - Bone Neoplasms KW - Pediatrics KW - Sarcoma KW - rare cancers KW - targeted therapy KW - pediatric oncology KW - dual pik3ca mtor inhibitors KW - pik3ca KW - spindle cell rhabdomyosarcoma KW - GNAS KW - molecularly targeted treatment KW - oncology TI - Investigating the therapeutic potential of molecularly targeted therapy in pediatric spindle cell rhabodmyosarcoma Y1 - 2020 L2 - https://digitalcollections.ohsu.edu/record/8279/files/Choo_Presentation.pdf L2 - https://digitalcollections.ohsu.edu/record/8279/files/Florence-Choo.pdf LK - https://digitalcollections.ohsu.edu/record/8279/files/Choo_Presentation.pdf LK - https://digitalcollections.ohsu.edu/record/8279/files/Florence-Choo.pdf UR - https://digitalcollections.ohsu.edu/record/8279/files/Choo_Presentation.pdf UR - https://digitalcollections.ohsu.edu/record/8279/files/Florence-Choo.pdf ER -