000008279 001__ 8279
000008279 005__ 20240410125019.0
000008279 0247_ $$2DOI$$a10.6083/2514nm15p
000008279 037__ $$aIR
000008279 041__ $$aeng
000008279 245__ $$aInvestigating the therapeutic potential of molecularly targeted therapy in pediatric spindle cell rhabodmyosarcoma
000008279 260__ $$bOregon Health and Science University
000008279 269__ $$a2020
000008279 336__ $$aAbstract
000008279 520__ $$aSarcoma is a cancer arising in the bone, connective, or soft-tissue and occurs at any age. Among these, spindle cell rhabdomyosarcoma (SCR) is a rare, aggressive skeletal muscle subtype predominately noted in children. Patients with SCR have poor outcomes despite intensive chemotherapy and radiation treatments, which emphasizes the need to understand tumor biology and identify molecularly targetable treatment options.
000008279 540__ $$fCC BY
000008279 542__ $$fIn copyright - joint owners
000008279 650__ $$aBone Neoplasms$$015731
000008279 650__ $$aPediatrics$$023687
000008279 650__ $$aSarcoma$$025711
000008279 6531_ $$arare cancers
000008279 6531_ $$atargeted therapy
000008279 6531_ $$apediatric oncology
000008279 6531_ $$adual pik3ca mtor inhibitors
000008279 6531_ $$apik3ca
000008279 6531_ $$aspindle cell rhabdomyosarcoma
000008279 6531_ $$aGNAS
000008279 6531_ $$amolecularly targeted treatment
000008279 6531_ $$aoncology
000008279 7001_ $$aChoo, Florence$$uOregon Health and Science University$$041354
000008279 7001_ $$aDavare, Monika$$uOregon Health and Science University$$041354
000008279 711__ $$aResearch Week$$uOregon Health and Science University$$d2020
000008279 8564_ $$987f59631-b54d-4bc5-b3f1-acf0d54eb491$$s1891000$$uhttps://digitalcollections.ohsu.edu/record/8279/files/Choo_Presentation.pdf
000008279 8564_ $$96d0db94e-dfbb-4f71-8a4f-dab23e57db0d$$s48914$$uhttps://digitalcollections.ohsu.edu/record/8279/files/Florence-Choo.pdf
000008279 905__ $$a/rest/prod/25/14/nm/15/2514nm15p
000008279 980__ $$aResearch Week