TY - GEN N2 - Articular cartilage has a very poor regeneration potential following injury, and former dogma held that it contains no progenitor cells. However, in recent years, articular cartilage progenitor (ACP) cells, which have the ability to produce stable articular cartilage in vitro, have been isolated and cloned from the tissue. However, we have found a subset of ACPs that undergo hypertrophic chondrogenesis, indicative of an endochondral chondrocyte phenotype. This study aimed to understand where this subset of ACPs reside in the tissue. DO - 10.6083/k0698807d DO - DOI AB - Articular cartilage has a very poor regeneration potential following injury, and former dogma held that it contains no progenitor cells. However, in recent years, articular cartilage progenitor (ACP) cells, which have the ability to produce stable articular cartilage in vitro, have been isolated and cloned from the tissue. However, we have found a subset of ACPs that undergo hypertrophic chondrogenesis, indicative of an endochondral chondrocyte phenotype. This study aimed to understand where this subset of ACPs reside in the tissue. AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University T1 - Location-specific differentiation potential of clonal articular cartilage progenitor cells DA - 2020 AU - Snyder, Leah AU - Lam, Phillip AU - Elhance, Ajit AU - Weekes, Kenneth AU - Kruckel, Jonas L1 - https://digitalcollections.ohsu.edu/record/8284/files/Snyder_Presentation.pdf L1 - https://digitalcollections.ohsu.edu/record/8284/files/Leah-Snyder.pdf PB - Oregon Health and Science University PY - 2020 ID - 8284 L4 - https://digitalcollections.ohsu.edu/record/8284/files/Snyder_Presentation.pdf L4 - https://digitalcollections.ohsu.edu/record/8284/files/Leah-Snyder.pdf KW - Regenerative Medicine KW - Tissue Engineering KW - Cartilage, Articular KW - Osteoarthritis KW - Arthritis KW - articular cartilage progenitor cells KW - joint tissue TI - Location-specific differentiation potential of clonal articular cartilage progenitor cells Y1 - 2020 L2 - https://digitalcollections.ohsu.edu/record/8284/files/Snyder_Presentation.pdf L2 - https://digitalcollections.ohsu.edu/record/8284/files/Leah-Snyder.pdf LK - https://digitalcollections.ohsu.edu/record/8284/files/Snyder_Presentation.pdf LK - https://digitalcollections.ohsu.edu/record/8284/files/Leah-Snyder.pdf UR - https://digitalcollections.ohsu.edu/record/8284/files/Snyder_Presentation.pdf UR - https://digitalcollections.ohsu.edu/record/8284/files/Leah-Snyder.pdf ER -