000008284 001__ 8284 000008284 005__ 20240411115609.0 000008284 0247_ $$2DOI$$a10.6083/k0698807d 000008284 037__ $$aIR 000008284 245__ $$aLocation-specific differentiation potential of clonal articular cartilage progenitor cells 000008284 260__ $$bOregon Health and Science University 000008284 269__ $$a2020 000008284 336__ $$aAbstract 000008284 520__ $$aArticular cartilage has a very poor regeneration potential following injury, and former dogma held that it contains no progenitor cells. However, in recent years, articular cartilage progenitor (ACP) cells, which have the ability to produce stable articular cartilage in vitro, have been isolated and cloned from the tissue. However, we have found a subset of ACPs that undergo hypertrophic chondrogenesis, indicative of an endochondral chondrocyte phenotype. This study aimed to understand where this subset of ACPs reside in the tissue. 000008284 540__ $$fCC BY 000008284 542__ $$fIn copyright - joint owners 000008284 650__ $$aRegenerative Medicine$$035572 000008284 650__ $$aTissue Engineering$$033051 000008284 650__ $$aCartilage, Articular$$016190 000008284 650__ $$aOsteoarthritis$$023338 000008284 650__ $$aArthritis$$015092 000008284 6531_ $$aarticular cartilage progenitor cells 000008284 6531_ $$ajoint tissue 000008284 7001_ $$aSnyder, Leah$$uOregon Health and Science University$$041354 000008284 7001_ $$aLam, Phillip$$uOregon Health and Science University$$041354 000008284 7001_ $$aElhance, Ajit$$uOregon Health and Science University$$041354 000008284 7001_ $$aWeekes, Kenneth$$uOregon Health and Science University$$041354 000008284 7001_ $$aKruckel, Jonas$$uOregon Health and Science University$$041354 000008284 711__ $$aResearch Week$$uOregon Health and Science University$$d2020 000008284 8564_ $$9f474d079-48df-4108-8ca4-be0417185c0a$$s773035$$uhttps://digitalcollections.ohsu.edu/record/8284/files/Snyder_Presentation.pdf 000008284 8564_ $$90f52ace9-98c9-436a-bc07-a9b5e247c089$$s48640$$uhttps://digitalcollections.ohsu.edu/record/8284/files/Leah-Snyder.pdf 000008284 905__ $$a/rest/prod/k0/69/88/07/k0698807d 000008284 980__ $$aResearch Week