TY - GEN N2 - During neuronal development, neuronal subtype differentiation is regulated by transcription factors (TF's) which control effector genes that define cell fate. TFs can regulate initial neuronal specification, the development of cell features (morphology, neurotransmitter expression, physiology) or both. The mammalian retina consists of 5 classes of retinal neurons with each type containing many subtypes. Detailing the specific roles TFs have in neuronal subtype specification and differentiation is important for understanding how neural circuitry develops and how morphological properties contribute to overall circuit function. DO - 10.6083/pn89d716g DO - DOI AB - During neuronal development, neuronal subtype differentiation is regulated by transcription factors (TF's) which control effector genes that define cell fate. TFs can regulate initial neuronal specification, the development of cell features (morphology, neurotransmitter expression, physiology) or both. The mammalian retina consists of 5 classes of retinal neurons with each type containing many subtypes. Detailing the specific roles TFs have in neuronal subtype specification and differentiation is important for understanding how neural circuitry develops and how morphological properties contribute to overall circuit function. AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University T1 - Isl1 is required for the specification and the morphological maturation of starburst amacrine cells DA - 2020 AU - Santana, Yessica AU - Stackhouse, Teresa AU - Kerstein, Patrick L1 - https://digitalcollections.ohsu.edu/record/8313/files/ResearchWeek.2020.Santana.Yessica.pdf PB - Oregon Health and Science University PY - 2020 ID - 8313 L4 - https://digitalcollections.ohsu.edu/record/8313/files/ResearchWeek.2020.Santana.Yessica.pdf KW - Transcription Factors KW - Amacrine Cells KW - neurodevelopment KW - starburst amacrine cell KW - Retina KW - cell fate TI - Isl1 is required for the specification and the morphological maturation of starburst amacrine cells Y1 - 2020 L2 - https://digitalcollections.ohsu.edu/record/8313/files/ResearchWeek.2020.Santana.Yessica.pdf LK - https://digitalcollections.ohsu.edu/record/8313/files/ResearchWeek.2020.Santana.Yessica.pdf UR - https://digitalcollections.ohsu.edu/record/8313/files/ResearchWeek.2020.Santana.Yessica.pdf ER -