000008313 001__ 8313 000008313 005__ 20240411095232.0 000008313 0247_ $$2DOI$$a10.6083/pn89d716g 000008313 037__ $$aIR 000008313 245__ $$aIsl1 is required for the specification and the morphological maturation of starburst amacrine cells 000008313 260__ $$bOregon Health and Science University 000008313 269__ $$a2020 000008313 336__ $$aAbstract 000008313 520__ $$aDuring neuronal development, neuronal subtype differentiation is regulated by transcription factors (TF's) which control effector genes that define cell fate. TFs can regulate initial neuronal specification, the development of cell features (morphology, neurotransmitter expression, physiology) or both. The mammalian retina consists of 5 classes of retinal neurons with each type containing many subtypes. Detailing the specific roles TFs have in neuronal subtype specification and differentiation is important for understanding how neural circuitry develops and how morphological properties contribute to overall circuit function. 000008313 540__ $$fCC BY 000008313 542__ $$fIn copyright - joint owners 000008313 650__ $$aTranscription Factors 000008313 650__ $$aAmacrine Cells$$033165 000008313 6531_ $$aneurodevelopment 000008313 6531_ $$astarburst amacrine cell 000008313 6531_ $$aRetina 000008313 6531_ $$acell fate 000008313 692__ $$aVollum Institute$$041509 000008313 7001_ $$aSantana, Yessica$$uOregon Health and Science University$$041354 000008313 7001_ $$aStackhouse, Teresa$$uOregon Health and Science University$$041354 000008313 7001_ $$aKerstein, Patrick$$uOregon Health and Science University$$041354 000008313 711__ $$aResearch Week$$uOregon Health and Science University$$d2020 000008313 8564_ $$9f7903191-9862-40d8-8d41-44c001721fa1$$s44423$$uhttps://digitalcollections.ohsu.edu/record/8313/files/ResearchWeek.2020.Santana.Yessica.pdf 000008313 905__ $$a/rest/prod/pn/89/d7/16/pn89d716g 000008313 980__ $$aResearch Week