000008319 001__ 8319 000008319 005__ 20240305154230.0 000008319 0247_ $$2DOI$$a10.6083/5x21tg07b 000008319 037__ $$aIR 000008319 041__ $$aeng 000008319 245__ $$aA scientific investigation into the therapeutic and adverse effects of cannabis 000008319 260__ $$bOregon Health and Science University 000008319 269__ $$a2020 000008319 336__ $$aAbstract 000008319 520__ $$aAmid spreading legalization of cannabis nationwide, the use of the drug for medicinal or recreation purpose alike is becoming increasingly commonplace. From customized cultivation practices to pharmaceutical developments, cannabis has changed from an illicit substance to a drug used for purposes of both therapy and indulgence. More data are becoming available pertaining to drug pharmacodynamics and pharmacokinetics, which may help guide clinical practices, and better define intoxication, toxicity, and safety profiles. The purpose of this conceptual framework is to briefly explore the pharmacology, demographics, and systematically-weighted evidenced-based therapeutic and adverse effects of cannabis (using the Scottish Intercollegiate Guidelines); highlight clinical, individual, and public implications related to cannabis use, dependence, and abuse; and identify gaps in the literature that could influence research in the future. 000008319 540__ $$fCC BY 000008319 542__ $$fIn copyright - single owner 000008319 650__ $$aPublic Health$$024885 000008319 650__ $$aClinical Nursing Research$$028382 000008319 650__ $$aCannabis$$016026 000008319 650__ $$aSubstance-Related Disorders$$032029 000008319 650__ $$aMarijuana Abuse$$016027 000008319 650__ $$aCannabinoids$$016024 000008319 650__ $$aMarijuana Smoking$$021841 000008319 6531_ $$amarijuana 000008319 691__ $$aSchool of Nursing$$041370 000008319 7001_ $$aAebischer, Jonathan$$uOregon Health and Science University$$041354 000008319 711__ $$aResearch Week$$uOregon Health and Science University$$d2020 000008319 8564_ $$9af796f12-f34c-4219-a09c-a6c79868b4ca$$s42388$$uhttps://digitalcollections.ohsu.edu/record/8319/files/ResearchWeek.2020.Aebischer.Jonathan.pdf 000008319 905__ $$a/rest/prod/5x/21/tg/07/5x21tg07b 000008319 980__ $$aResearch Week