@article{IR,
      recid = {8350},
      author = {Schaser, Allison and Stackhouse, Teresa and Meshul,  Charlie and Lopez, Claudia S. and Unni, Vivek},
      title = {Transport of alpha-synuclein fibril aggregates in an in  vivo mouse model of Parkinson's disease},
      publisher = {Oregon Health and Science University},
      address = {2020},
      number = {IR},
      abstract = {Parkinson's disease (PD) is a progressive  neurodegenerative disorder for which there are currently no  treatments to slow, halt, or reverse the disease process.  The disease is defined by the accumulation of the protein  alpha-synuclein into aggregates known as Lewy inclusions,  but how these aggregates initiate and propagate to various  locations throughout the brain is unknown. To develop  targeted disease modifying therapies, it is important to  understand how aggregated forms of alpha-synuclein are  transported throughout the nervous system and to determine  the effect aggregation of alpha-synuclein has on specific  cell types and specific behaviors. The hypotheses of this  research are that alpha-synuclein aggregates propagate  through neuroanatomically connected pathways and that  induction of Lewy pathology results in behavioral  deficits.},
      url = {http://digitalcollections.ohsu.edu/record/8350},
      doi = {https://doi.org/10.6083/4f16c363r},
}