@article{IR, recid = {8353}, author = {França, Cristiane M. and Tahayeri, Anthony and Mansoorifar, Amin and Rodrigues, Nara and Cunha, Diana and Ferracane, Jack and Kreth, Jens and Bertassoni, Luiz E.}, title = {The tooth on-a-chip as model of dental pulp cell response to biomaterials and oral biolfim}, publisher = {Oregon Health and Science University}, address = {2020}, number = {IR}, abstract = {There is a shortage of in-vitro model systems that mimic the dentin-pulp interface while enabling a real-time evaluation of dental pulp cells, dentin and biomaterials. Here, we optimized an organ-on-a-chip model system, the "Tooth-on-a-chip" and tested different biomaterials in real-time. Moreover, we developed a model of secondary caries on-chip co-culturing oral microcosm with dental pulp cells.}, url = {http://digitalcollections.ohsu.edu/record/8353}, doi = {https://doi.org/10.6083/3f4626013}, }