TY  - GEN
N2  - There is a shortage of in-vitro model systems that mimic the dentin-pulp interface while enabling a real-time evaluation of dental pulp cells, dentin and biomaterials. Here, we optimized an organ-on-a-chip model system, the "Tooth-on-a-chip" and tested different biomaterials in real-time. Moreover, we developed a model of secondary caries on-chip co-culturing oral microcosm with dental pulp cells.
DO  - 10.6083/3f4626013
DO  - DOI
AB  - There is a shortage of in-vitro model systems that mimic the dentin-pulp interface while enabling a real-time evaluation of dental pulp cells, dentin and biomaterials. Here, we optimized an organ-on-a-chip model system, the "Tooth-on-a-chip" and tested different biomaterials in real-time. Moreover, we developed a model of secondary caries on-chip co-culturing oral microcosm with dental pulp cells.
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
T1  - The tooth on-a-chip as model of dental pulp cell response to biomaterials and oral biolfim
DA  - 2020
AU  - França, Cristiane M.
AU  - Tahayeri, Anthony
AU  - Mansoorifar, Amin
AU  - Rodrigues, Nara
AU  - Cunha, Diana
AU  - Ferracane, Jack
AU  - Kreth, Jens
AU  - Bertassoni, Luiz E.
L1  - https://digitalcollections.ohsu.edu/record/8353/files/ResearchWeek.2020.Franca.Cristiane.pdf
PB  - Oregon Health and Science University
PY  - 2020
ID  - 8353
L4  - https://digitalcollections.ohsu.edu/record/8353/files/ResearchWeek.2020.Franca.Cristiane.pdf
KW  - Dentistry
KW  - Dental Pulp
KW  - Biocompatible Materials
KW  - Microphysiological Systems
KW  - Dentin
KW  - Dental Caries
KW  - dentin-pulp interface
TI  - The tooth on-a-chip as model of dental pulp cell response to biomaterials and oral biolfim
Y1  - 2020
L2  - https://digitalcollections.ohsu.edu/record/8353/files/ResearchWeek.2020.Franca.Cristiane.pdf
LK  - https://digitalcollections.ohsu.edu/record/8353/files/ResearchWeek.2020.Franca.Cristiane.pdf
UR  - https://digitalcollections.ohsu.edu/record/8353/files/ResearchWeek.2020.Franca.Cristiane.pdf
ER  -