000008360 001__ 8360
000008360 005__ 20240418090904.0
000008360 0247_ $$2DOI$$a10.6083/8049g5613
000008360 037__ $$aIR
000008360 245__ $$aTo flow or not to flow: considerations for quantitative microbiome profiling
000008360 260__ $$bOregon Health and Science University
000008360 269__ $$a2020
000008360 336__ $$aAbstract
000008360 520__ $$aCulture-independent methods are changing the way scientists interrogate microbes in complex environments such as the human body. Specifically, targeted sequencing of the conserved 16S rRNA gene is relatively simple, inexpensive, and high-throughput. However, the analysis of such data quantifies each microbe as a fraction of the total read count, which can lead to misinterpretations of microbes that differ between communities associated with disease. To address this limitation, quantitative microbiome profiling (QMP) methods have been developed.
000008360 540__ $$fCC BY
000008360 542__ $$fIn copyright - joint owners
000008360 6531_ $$aquantitative microbiome profiling
000008360 6531_ $$amicrobial load
000008360 6531_ $$a16S rRNA gene
000008360 6531_ $$amicrobiome
000008360 6531_ $$agene sequencing
000008360 691__ $$aSchool of Medicine$$041369
000008360 692__ $$aDepartment of Biomedical Engineering$$041397
000008360 692__ $$aCancer Early Detection Advanced Research Center$$041380
000008360 7001_ $$aBowie, Kathleen$$uOregon Health and Science University$$041354
000008360 7001_ $$aFurst, Alec$$uOregon Health and Science University$$041354
000008360 7001_ $$aSchleisman, Matt$$uOregon Health and Science University$$041354
000008360 7001_ $$aJallow, Fatoumata$$uOregon Health and Science University$$041354
000008360 7001_ $$aDavin, Sean$$uOregon Health and Science University$$041354
000008360 7001_ $$aRosenbaum, James T.$$uOregon Health and Science University$$041354
000008360 7001_ $$aKarstens, Lisa$$uOregon Health and Science University$$041354
000008360 711__ $$aResearch Week$$uOregon Health and Science University$$d2020
000008360 8564_ $$91024ca20-b7e7-435f-b294-cf9050ec5267$$s45596$$uhttps://digitalcollections.ohsu.edu/record/8360/files/ResearchWeek.2020.Bowie.Kathleen.pdf
000008360 905__ $$a/rest/prod/80/49/g5/61/8049g5613
000008360 980__ $$aResearch Week