TY  - GEN
AB  - Sleep deprivation studies indicate an essential role for sleep in the pathophysiology of many conditions, with sleep at a lifetime maximum during early life. Previous research in our lab using an early life sleep disruption (ELSD) paradigm has shown long lasting deficits in complex social and cognitive behaviors in adult prairie voles. We hypothesized that increased time spent awake during ELSD may cause a transient increase in excitatory neurotransmission, leading to morphological changes in dendritic spines and long lasting changes in excitatory neurotransmission
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AU  - Olson, Randall
AU  - Jones, Carolyn E.
AU  - Chau, Alex Q.
AU  - Puranik, Niyati
AU  - Moore, Cynthia
AU  - Wickham, Peyton T.
AU  - Meshul, Charles K.
AU  - Lim, Miranda M.
DA  - 2020
DO  - 10.6083/rf55z832m
DO  - DOI
ID  - 8365
KW  - Sleep Deprivation
KW  - early life sleep disruption
KW  - sleep health
KW  - sleep disruption
KW  - prairie voles
KW  - dendritic spikes
KW  - cognitive behaviors
KW  - excitatory neurotransmission
L1  - https://digitalcollections.ohsu.edu/record/8365/files/ResearchWeek.2020.Olson.Randall.pdf
L2  - https://digitalcollections.ohsu.edu/record/8365/files/ResearchWeek.2020.Olson.Randall.pdf
L4  - https://digitalcollections.ohsu.edu/record/8365/files/ResearchWeek.2020.Olson.Randall.pdf
LK  - https://digitalcollections.ohsu.edu/record/8365/files/ResearchWeek.2020.Olson.Randall.pdf
N2  - Sleep deprivation studies indicate an essential role for sleep in the pathophysiology of many conditions, with sleep at a lifetime maximum during early life. Previous research in our lab using an early life sleep disruption (ELSD) paradigm has shown long lasting deficits in complex social and cognitive behaviors in adult prairie voles. We hypothesized that increased time spent awake during ELSD may cause a transient increase in excitatory neurotransmission, leading to morphological changes in dendritic spines and long lasting changes in excitatory neurotransmission
PB  - Oregon Health and Science University
PY  - 2020
T1  - Dendritic spine morphology and excitatory neurotransmission in prefrontal cortex is altered after early life sleep disruption
TI  - Dendritic spine morphology and excitatory neurotransmission in prefrontal cortex is altered after early life sleep disruption
UR  - https://digitalcollections.ohsu.edu/record/8365/files/ResearchWeek.2020.Olson.Randall.pdf
Y1  - 2020
ER  -