TY - GEN N2 - Administration of chemotherapy via intra-arterial (IA) route results in a higher concentration of targeted chemotherapy against resilient brain malignancies with a decreased systemic chemotherapy side effect. Osmotic blood-brain barrier disruption (BBBD) further intensify drug delivery and effects on brain malignancies. The aim of this study is to determine the safety of the use of intra-arterial chemotherapy and blood brain barrier disruption to treat malignant brain tumors. DO - 10.6083/cv43nx55c DO - DOI AB - Administration of chemotherapy via intra-arterial (IA) route results in a higher concentration of targeted chemotherapy against resilient brain malignancies with a decreased systemic chemotherapy side effect. Osmotic blood-brain barrier disruption (BBBD) further intensify drug delivery and effects on brain malignancies. The aim of this study is to determine the safety of the use of intra-arterial chemotherapy and blood brain barrier disruption to treat malignant brain tumors. AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University T1 - Safety of intra-arterial (IA) chemotherapy and blood brain barrier disruption (BBBD) for treatment of patients with malignant brain tumors DA - 2020 AU - Tabb, John AU - Ambady, Prakash AU - Neuwelt, Edward AU - Uluc, Kutluay L1 - https://digitalcollections.ohsu.edu/record/8372/files/ResearchWeek.2020.UlucKutluay.pdf PB - Oregon Health and Science University PY - 2020 ID - 8372 L4 - https://digitalcollections.ohsu.edu/record/8372/files/ResearchWeek.2020.UlucKutluay.pdf KW - Drug Therapy KW - Blood-Brain Barrier KW - Brain Neoplasms KW - brain tumors KW - intra-arterial chemotherapy KW - cancer KW - blood brain barrier disruption KW - chemotherapy TI - Safety of intra-arterial (IA) chemotherapy and blood brain barrier disruption (BBBD) for treatment of patients with malignant brain tumors Y1 - 2020 L2 - https://digitalcollections.ohsu.edu/record/8372/files/ResearchWeek.2020.UlucKutluay.pdf LK - https://digitalcollections.ohsu.edu/record/8372/files/ResearchWeek.2020.UlucKutluay.pdf UR - https://digitalcollections.ohsu.edu/record/8372/files/ResearchWeek.2020.UlucKutluay.pdf ER -