000008372 001__ 8372
000008372 005__ 20240415155725.0
000008372 0247_ $$2DOI$$a10.6083/cv43nx55c
000008372 037__ $$aIR
000008372 245__ $$aSafety of intra-arterial (IA) chemotherapy and blood brain barrier disruption (BBBD) for treatment of patients with malignant brain tumors
000008372 260__ $$bOregon Health and Science University
000008372 269__ $$a2020
000008372 336__ $$aAbstract
000008372 520__ $$aAdministration of chemotherapy via intra-arterial (IA) route results in a higher concentration of targeted chemotherapy against resilient brain malignancies with a decreased systemic chemotherapy side effect. Osmotic blood-brain barrier disruption (BBBD) further intensify drug delivery and effects on brain malignancies. The aim of this study is to determine the safety of the use of intra-arterial chemotherapy and blood brain barrier disruption to treat malignant brain tumors.
000008372 540__ $$fCC BY
000008372 542__ $$fIn copyright - joint owners
000008372 650__ $$aDrug Therapy$$018086
000008372 650__ $$aBlood-Brain Barrier$$015687
000008372 650__ $$aBrain Neoplasms$$015799
000008372 6531_ $$abrain tumors
000008372 6531_ $$aintra-arterial chemotherapy
000008372 6531_ $$acancer
000008372 6531_ $$ablood brain barrier disruption
000008372 6531_ $$achemotherapy
000008372 691__ $$aSchool of Medicine$$041369
000008372 692__ $$aDivision of Hematology and Medical Oncology$$041461
000008372 7001_ $$aTabb, John$$uOregon Health and Science University$$041354
000008372 7001_ $$aAmbady, Prakash$$uOregon Health and Science University$$041354
000008372 7001_ $$aNeuwelt, Edward$$uOregon Health and Science University$$041354
000008372 7001_ $$aUluc, Kutluay$$uOregon Health and Science University$$041354
000008372 711__ $$aResearch Week$$uOregon Health and Science University$$d2022
000008372 8564_ $$9f0c79615-7cf5-431e-9e75-ef1061ac68b7$$s44261$$uhttps://digitalcollections.ohsu.edu/record/8372/files/ResearchWeek.2020.UlucKutluay.pdf
000008372 905__ $$a/rest/prod/cv/43/nx/55/cv43nx55c
000008372 980__ $$aResearch Week