000008376 001__ 8376
000008376 005__ 20240411115039.0
000008376 0247_ $$2DOI$$a10.6083/9w032363r
000008376 037__ $$aIR
000008376 245__ $$aLinking traumatic brain injury, and post-traumatic headache: a potential role for glymphatic pathway dysfunction
000008376 260__ $$bOregon Health and Science University
000008376 269__ $$a2020
000008376 336__ $$aAbstract
000008376 520__ $$aHeadaches are frequently reported by patients with traumatic brain injury (TBI). The relationship between TBI and headaches is poorly understood. Disruption of the glymphatic pathway, a brain-wide network of perivascular spaces, could explain this link. The glymphatic pathway allows the exchange of fluid, solutes, and wastes between the cerebrospinal fluid and the brain interstitium. MRI-visible enlarged perivascular spaces (ePVS) may be putative surrogates of glymphatic function. The purpose of this study is to: a) characterize the ePVS burden in a cohort of healthy adolescents; b) determine if ePVS burden is increased in individuals with post-concussive symptoms.
000008376 540__ $$fCC BY
000008376 542__ $$fIn copyright - joint owners
000008376 650__ $$aMagnetic Resonance Imaging$$021747
000008376 650__ $$aBrain Concussion$$015791
000008376 650__ $$aHeadache$$019869
000008376 650__ $$aGlymphatic System$$012789
000008376 650__ $$apediatrics
000008376 6531_ $$atraumatic brain injury
000008376 6531_ $$aMRI
000008376 6531_ $$aenlarged perivascular spaces
000008376 691__ $$aSchool of Medicine$$041369
000008376 692__ $$aDepartment of Emergency Medicine$$041411
000008376 7001_ $$aCenteno, Luis D.L.$$uOregon Health and Science University$$041354
000008376 7001_ $$aLuther, Madison$$uOregon Health and Science University$$041354
000008376 7001_ $$aNagel, Bonnie$$uOregon Health and Science University$$041354
000008376 7001_ $$aSchwartz, Daniel$$uOregon Health and Science University$$041354
000008376 7001_ $$aNewgard, Craig$$uOregon Health and Science University$$041354
000008376 7001_ $$aPiantino, Juan$$uOregon Health and Science University$$041354
000008376 711__ $$aResearch Week$$uOregon Health and Science University
000008376 8564_ $$91fadfcff-990f-43f0-bf84-f045eee445ae$$s44994$$uhttps://digitalcollections.ohsu.edu/record/8376/files/ResearchWeek.2020.Centeno.Luis.pdf
000008376 905__ $$a/rest/prod/9w/03/23/63/9w032363r
000008376 980__ $$aResearch Week