TY  - GEN
N2  - Abnormal splicing events can promote drug resistance in a variety of cancer types, however, the full extent of genome-wide splicing in therapy-resistant AML is not fully characterized. This research utilizes a network-based approach to characterize coordinated alternative splicing variation and identify potential splicing event signatures of drug response in AML.
DO  - 10.6083/pr76f412m
DO  - DOI
AB  - Abnormal splicing events can promote drug resistance in a variety of cancer types, however, the full extent of genome-wide splicing in therapy-resistant AML is not fully characterized. This research utilizes a network-based approach to characterize coordinated alternative splicing variation and identify potential splicing event signatures of drug response in AML.
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
T1  - Transcriptome-wide characterization of alternative splicing variants in drug resistant AML
DA  - 2020
AU  - Egger, Julian
AU  - Zheng, Christina
AU  - McWeeney, Shannon
AU  - Wu, Guanming
AU  - Laderas, Ted
AU  - Hitzemann, Robert
L1  - https://digitalcollections.ohsu.edu/record/8391/files/ResearchWeek.2020.Egger.Julian.pdf
PB  - Oregon Health and Science University
LA  - eng
PY  - 2020
ID  - 8391
L4  - https://digitalcollections.ohsu.edu/record/8391/files/ResearchWeek.2020.Egger.Julian.pdf
KW  - Computational Biology
KW  - Genomics
KW  - Alternative Splicing
KW  - RNA-Seq
KW  - Leukemia, Myeloid, Acute
KW  - Drug Resistance
KW  - bioinformatics
KW  - neoplasms
KW  - cancer
TI  - Transcriptome-wide characterization of alternative splicing variants in drug resistant AML
Y1  - 2020
L2  - https://digitalcollections.ohsu.edu/record/8391/files/ResearchWeek.2020.Egger.Julian.pdf
LK  - https://digitalcollections.ohsu.edu/record/8391/files/ResearchWeek.2020.Egger.Julian.pdf
UR  - https://digitalcollections.ohsu.edu/record/8391/files/ResearchWeek.2020.Egger.Julian.pdf
ER  -