000008391 001__ 8391
000008391 005__ 20240418103312.0
000008391 0247_ $$2DOI$$a10.6083/pr76f412m
000008391 037__ $$aIR
000008391 041__ $$aeng
000008391 245__ $$aTranscriptome-wide characterization of alternative splicing variants in drug resistant AML
000008391 260__ $$bOregon Health and Science University
000008391 269__ $$a2020
000008391 336__ $$aAbstract
000008391 520__ $$aAbnormal splicing events can promote drug resistance in a variety of cancer types, however, the full extent of genome-wide splicing in therapy-resistant AML is not fully characterized. This research utilizes a network-based approach to characterize coordinated alternative splicing variation and identify potential splicing event signatures of drug response in AML.
000008391 540__ $$fCC BY
000008391 542__ $$fIn copyright - joint owners
000008391 650__ $$aComputational Biology$$031511
000008391 650__ $$aGenomics$$033016
000008391 650__ $$aAlternative Splicing$$029939
000008391 650__ $$aRNA-Seq$$013251
000008391 650__ $$aLeukemia, Myeloid, Acute$$028432
000008391 650__ $$aDrug Resistance$$018079
000008391 6531_ $$abioinformatics
000008391 6531_ $$aneoplasms
000008391 6531_ $$acancer
000008391 691__ $$aSchool of Medicine$$041369
000008391 692__ $$aDepartment of Medical Informatics and Clinical Epidemiology$$041422
000008391 7001_ $$aEgger, Julian$$uOregon Health and Science University$$041354
000008391 7001_ $$aZheng, Christina$$uOregon Health and Science University$$041354
000008391 7001_ $$aMcWeeney, Shannon$$uOregon Health and Science University$$041354
000008391 7001_ $$aWu, Guanming$$uOregon Health and Science University$$041354
000008391 7001_ $$aLaderas, Ted$$uOregon Health and Science University$$041354
000008391 7001_ $$aHitzemann, Robert$$uOregon Health and Science University$$041354
000008391 711__ $$aResearch Week$$uOregon Health and Science University$$d2020
000008391 8564_ $$90d63b93c-25e1-4fd9-8f2e-351a6148ab6e$$s39820$$uhttps://digitalcollections.ohsu.edu/record/8391/files/ResearchWeek.2020.Egger.Julian.pdf
000008391 905__ $$a/rest/prod/pr/76/f4/12/pr76f412m
000008391 980__ $$aResearch Week