TY  - GEN
N2  - Long-chain 3-Hydroxyacyl CoA Dehydrogenase Deficiency (LCHADD) is an autosomal recessive defect in fatty acid oxidation that presents with hypoketotic hypoglycemia and/or hypertrophic cardiomyopathy in infancy, and recurrent rhabdomyolysis in adolescence, however, sudden cardiac death has not been a previously reported complication of LCHADD. We have conducted a case review study comparing young adult LCHADD patients who have experienced sudden cardiac arrest events (n=5) to similar patients who have not (n=5) for the purpose of evaluating associated cardiac risk factors.
DO  - 10.6083/cj82k793z
DO  - DOI
AB  - Long-chain 3-Hydroxyacyl CoA Dehydrogenase Deficiency (LCHADD) is an autosomal recessive defect in fatty acid oxidation that presents with hypoketotic hypoglycemia and/or hypertrophic cardiomyopathy in infancy, and recurrent rhabdomyolysis in adolescence, however, sudden cardiac death has not been a previously reported complication of LCHADD. We have conducted a case review study comparing young adult LCHADD patients who have experienced sudden cardiac arrest events (n=5) to similar patients who have not (n=5) for the purpose of evaluating associated cardiac risk factors.
AD  - OHSU/PSU
AD  - Oregon Health and Science University
T1  - Sudden cardiac death in young adults with long-chain 3-hydroxyacyl coa dehydrogenase deficiency (LCHADD)
ED  - Devine, Tiffany
ED  - Collaborator
DA  - 2020
AU  - Saini, Ajesh
AU  - Gonzales-De Alba, Cesar
L1  - https://digitalcollections.ohsu.edu/record/8416/files/ResearchWeek.2020.Saini.Ajesh.pdf
PB  - Oregon Health and Science University
LA  - eng
PY  - 2020
ID  - 8416
L4  - https://digitalcollections.ohsu.edu/record/8416/files/ResearchWeek.2020.Saini.Ajesh.pdf
KW  - Death, Sudden, Cardiac
KW  - Stem Cell Research
KW  - Cardiology
KW  - Fatty Acids
KW  - Myocardial Infarction
KW  - Rare Diseases
KW  - Adolescent
KW  - Young Adult
KW  - Cardiomyopathy, Hypertrophic
KW  - Risk Factors
KW  - fatty acid oxidation disorders
KW  - LCHAD deficiency
KW  - heart attack
KW  - genetic diseases
TI  - Sudden cardiac death in young adults with long-chain 3-hydroxyacyl coa dehydrogenase deficiency (LCHADD)
Y1  - 2020
L2  - https://digitalcollections.ohsu.edu/record/8416/files/ResearchWeek.2020.Saini.Ajesh.pdf
LK  - https://digitalcollections.ohsu.edu/record/8416/files/ResearchWeek.2020.Saini.Ajesh.pdf
UR  - https://digitalcollections.ohsu.edu/record/8416/files/ResearchWeek.2020.Saini.Ajesh.pdf
ER  -